产品介绍
BioXcell InVivoPlus anti-mouse Ly6G 1A8单克隆抗体与小鼠Ly6G反应。Ly6G分子量为21-25kDa,是GPI锚定的细胞表面蛋白Ly-6超家族的成员,在细胞信号传导和细胞粘附中发挥作用。Ly6G在发育过程中由骨髓谱系中的细胞(包括单核细胞、巨噬细胞、粒细胞和嗜中性粒细胞)差异表达。单核细胞通常在发育过程中瞬时表达Ly6G,而成熟的粒细胞和外周嗜中性粒细胞保持表达,使Ly6G成为这些群体的良好细胞表面标志物。与BioXcell RB6-8C5抗体不同,1A8抗体与小鼠Ly6G特异性反应,而与Ly6C没有交叉反应性的报道。
产品详情
产品名称 |
InVivoPlus anti-mouse Ly6G |
产品货号 |
BP0075-1 |
产品规格 |
5/25/50/100mg |
反应种属 |
Mouse |
克隆号 |
1A8 |
同种型 |
Rat IgG2a, κ |
免疫原 |
EL4J cells transfected with Ly6G |
实验应用 |
in vivo neutrophil depletion in vivo MDSC depletion Immunofluorescence Immunohistochemistry (paraffin) Immunohistochemistry (frozen) Flow cytometry |
产品形式 |
PBS, pH 7.0,Contains no stabilizers or preservatives |
纯度 |
>95%, Determined by SDS-PAGE |
聚合 |
<5%, Determined by SEC |
无菌处理 |
0.2 µm filtration |
纯化方式 |
Protein G |
RRID |
AB_1107721 |
分子量 |
150 kDa |
小鼠病原检测 |
Ectromelia/Mousepox Virus: Negative Hantavirus: Negative K Virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Lymphocytic Choriomeningitis virus: Negative Mouse Adenovirus: Negative Mouse Cytomegalovirus: Negative Mouse Hepatitis Virus: Negative Mouse Minute Virus: Negative Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Rotavirus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Polyoma Virus: Negative Reovirus Screen: Negative Sendai Virus: Negative Theiler’s Murine Encephalomyelitis: Negative |
保存条件 |
抗体原液保存在4°C,不能冷冻保存。 |
推荐同型对照 |
InVivoPlus rat IgG2a isotype control, anti-trinitrophenol(货号BP0089) |
推荐抗体稀释液 |
InVivoPure pH 7.0 Dilution Buffer(货号IP0070) |
为什么选择InVivoPlus抗体?
InVivoPlus级别的产品内毒素含量更低,经过多种实验验证,更适合用于体内实验研究
该产品自上市已被多篇SCI文献引用,品质有保证,以下是部分已发表的文献引用:
应用 |
文章 |
体内中性粒细胞耗竭 (in vivo neutrophil depletion) |
1. Davis, R. W. t., et al. (2018). 'Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy' Photochem Photobiol . 2. Moynihan, K. D., et al. (2016). 'Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses' Nat Med. doi : 10.1038/nm.4200. 3. Conde, P., et al. (2015). 'DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance' Immunity 42(6): 1143-1158. 4. Griseri, T., et al. (2015). 'Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis' Immunity 43(1): 187-199. 5. Yamada, D. H., et al. (2015). 'Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection' Immunity 42(2): 379-390. 6. Ellis, G. T., et al. (2015). 'TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection' EMBO Rep 16(9): 1203-1218. 7. Deshmukh, H. S., et al. (2014). 'The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice' Nat Med 20(5): 524-530. |
体内中性粒细胞耗竭、流式细胞术、免疫组化石蜡切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin)) |
Coffelt, S. B., et al. (2015). 'IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis' Nature 522(7556): 345-348. |
体内中性粒细胞耗竭、流式细胞术、免疫组化石蜡切片、免疫组化冰冻切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen)) |
欣博盛生物科技有限公司 商家主页地 址: 深圳福田区梅华路105号多丽工业区科技楼605 联系人: Miss Yao 电 话: 0755-26755892(深圳) 010-88594029(北京) 021-34613729(上海) 020-87615159 (广州) 传 真: 0755-26755877 Email:market@neobioscience.com 相关咨询Enzo Life Sciences新品:HCP wash buffer (10X) /ENZ-ACC173-0100 (暂无发布时间 浏览数:8259) Chondrex代理商欣博盛生物:带你了解蛋白纯化 (暂无发布时间 浏览数:4585) Cayman Chemical欣博盛生物|葡萄糖代谢研究产品一览 (暂无发布时间 浏览数:8251) GeneTex热销抗体 — GAPDH抗体(克隆号GT239) (暂无发布时间 浏览数:7376) Demeditec Diagnostics DmbH兽医诊断类产品 (暂无发布时间 浏览数:6953) 如何挑选Cargille折射率匹配液? (暂无发布时间 浏览数:9462) Cell Biolabs代理欣博盛生物:如何检测细胞衰老? (暂无发布时间 浏览数:6783) 如何挑选合适的内参抗体? (暂无发布时间 浏览数:9567) Vectorlabs—VectaFluor™ Excel Amplified高灵敏二抗产品,低价促销 (暂无发布时间 浏览数:8366) Vectorlabs—ImmPRESS®多聚物双染试剂盒,低价促销 (暂无发布时间 浏览数:9648) ADVERTISEMENT
|