IL15RA monoclonal antibody, clone eBioJM7A4
产品名称: IL15RA monoclonal antibody, clone eBioJM7A4
英文名称: IL15RA monoclonal antibody, clone eBioJM7A4
产品编号: MAB10883
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against IL15RA.
- Immunogen:
- Human IL15RA.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- The monoclonal antibody reacts with IL15RA.
- Form:
- Liquid
- Purification:
- Affinity purification
- Isotype:
- IgG2b
- Storage Buffer:
- In aqueous buffer (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Flow Cytometry
- Staining of adherent human PBMCs stimulated with LPS and IFN gamma for 24 hours with 0.25 ug of mouse IgG2b kappa isotype control purified (open histogram) or 0.25 ug of IL15RA monoclonal antibody, clone eBioJM7A4 (Cat # MAB10883) (filled histogram) followed by Anti-mouse IgG biotin and streptavidin PE. Cells in the large scatter population were used for analysis.
- Entrez GeneID:
- 3601
- Gene Name:
- IL15RA
- Gene Alias:
- MGC104179
- Gene Description:
- interleukin 15 receptor, alpha
- Omim ID:
- 601070
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine receptor that specifically binds IL15 with high affinity. The receptors of IL15 and IL2 share two subunits, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. The full length sequences of only two variants encoding distinct isoforms are available. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019021,OTTHUMP00000019022
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