FITC标记的LARP1蛋白抗体
产品名称： FITC标记的LARP1蛋白抗体
英文名称： Anti-LARP1/FITC
产品编号： HZ-17101R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LARP1/FITC Conjugated antibody
FITC标记的LARP1蛋白抗体
| 英文名称 | Anti-LARP1/FITC |
| 中文名称 | FITC标记的LARP1蛋白抗体 |
| 别 名 | 1810024J12Rik; 3110040D16Rik; KIAA0731; La related protein; La ribonucleoprotein domain family, member 1; LARP; MGC19556; mKIAA0731; rCG_32791; RGD1306683; RP23-293I3.7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞凋亡 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 124kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LARP1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: LARP1 is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing. Function: LARP1 belongs to the LARP family and contains 1 HTH La-type RNA-binding domain. Subunit: Interacts with PABPC1/PABP. Associates with the mTORC1 complex. Interacts with EIF4E. Subcellular Location: Cytoplasm Similarity: Belongs to the LARP family. Contains 1 HTH La-type RNA-binding domain. Database links: Entrez Gene: 23367 Human Omim: 612059 Human SwissProt: Q6PKG0 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
LARP1是属于LARP家族的1096氨基酸蛋白。larp1含有两个保守区，一个与La / SSB蛋白和一个保守的蛋白家族的同源性在LARP股份。在La / SSB的保守区域，larp1包含HTH la型RNA结合结构域，这可能表明在RNA stabalization褶皱作用。DNA损伤后，ATRR或ATM磷酸化LARP1。LARP1与许多信号性中间蛋白相互作用，包括14-3-3。广泛表达的心脏中，LARP1水平最高。LARP1以选择性剪接产生的三种异构体存在。