FITC标记的4号染色体开放阅读框46抗体
产品名称： FITC标记的4号染色体开放阅读框46抗体
英文名称： Anti-C4orf46/FITC
产品编号： HZ-15194R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C4orf46/FITC Conjugated antibody
FITC标记的4号染色体开放阅读框46抗体
| 英文名称 | Anti-C4orf46/FITC |
| 中文名称 | FITC标记的4号染色体开放阅读框46抗体 |
| 别 名 | C4orf46; CD046_HUMAN; Chromosome 4 open reading frame 46; hypothetical protein LOC201725; Hypothetical protein LOC201725 2; Uncharacterized protein C4orf46. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 12kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C4orf46 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The C4orf46 gene product has been provisionally designated C4orf46 pending further characterization. Database links: Entrez Gene: 201725 Human SwissProt: Q504U0 Human Unigene: 380920 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
代表人类基因组的6%，4号染色体包含近900个基因。值得注意的是，亨廷顿基因位于第4染色体上，在亨廷顿病的病例中发现该基因编码扩张的谷氨酰胺束。FGFR-3还编码在第4号染色体上，并与丘脑侏儒症、软骨发育不良、Muenke综合征和膀胱癌有关。第4号染色体也与Ellis van Creveld综合征、甲基丙二酸血症和多囊肾病有关。据报道，染色体4包含最大的基因沙漠（基因组中没有蛋白质编码基因的区域），并且具有人类染色体的两个最低重组频率之一。C4OF46基因产物已暂时指定为C4OF46，有待进一步鉴定。