CYP46A1 monoclonal antibody (M01), clone 1A11
产品名称： CYP46A1 monoclonal antibody (M01), clone 1A11
英文名称： CYP46A1 monoclonal antibody (M01), clone 1A11
产品编号： H00010858-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CYP46A1.
- Immunogen:
- CYP46A1 (NP_006659, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVTFF
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CYP46A1 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 10858
- GeneBank Accession#:
- NM_006668
- Protein Accession#:
- NP_006659
- Gene Name:
- CYP46A1
- Gene Alias:
- CP46,CYP46
- Gene Description:
- cytochrome P450, family 46, subfamily A, polypeptide 1
- Omim ID:
- 604087
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq
- Other Designations:
- cholesterol 24-hydroxylase,cytochrome P450, family 46,cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Cognition Disorders
- Diabetes Complications
- Disease Progression
- Genetic Predisposition to Disease
- Macular Degeneration
- Mental Status Schedule
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis
- Postmortem Changes
- Psychiatric Status Rating Scales