Anti-BCL2L1 Polyclonal Antibody

K001595P-50ul	Solarbio	50ul	960.00元
K001595P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit BCL2L1 Polyclonal Antibody
应用2	WB IP IF
克隆类型2	Polyclonal Antibody
别名	BCL-XL/S;BCL2L;BCLX;Bcl-X;PPP1R52
应用	WB,IF,IP
稀释比例	WB1:500-1:2000 IF 1:50 - 1:200 IP 1:50 - 1:100
交叉反应	Human Mouse Rat
蛋白分子量	26kDa
Gene ID	598
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human BCL2L1
性状	Lyophilized or Liquid
Swiss Prot	Q07817
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.