Anti-TLR4 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司--实验室产品
Anti-TLR4 Polyclonal Antibody

Anti-TLR4 Polyclonal Antibody

商家询价

产品名称: Anti-TLR4 Polyclonal Antibody

英文名称: ARMD10;CD284;TLR-4;TOLL

产品编号: K002172P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: null

使用范围: WB

北京索莱宝科技有限公司--实验室产品
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.