TTBK2 (Human) Recombinant Protein
产品名称： TTBK2 (Human) Recombinant Protein
英文名称： TTBK2 (Human) Recombinant Protein
产品编号： P5658
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human TTBK2 (NP_775771.3, 1 a.a. - 331 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 64
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf21) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 98 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: GS peptide. ATP: 100 uM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 146057
- Protein Accession#:
- NP_775771.3
- Gene Name:
- TTBK2
- Gene Alias:
- KIAA0847,SCA11,TTBK
- Gene Description:
- tau tubulin kinase 2
- Omim ID:
- 604432
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. [provided by RefSeq
- Other Designations:
- spinocerebellar ataxia 11,tau-tubulin kinase
- Related Disease