FITC标记的蛛毒素受体2抗体
产品名称： FITC标记的蛛毒素受体2抗体
英文名称： Anti-LPHN2/FITC
产品编号： HZ-18349R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LPHN2/FITC Conjugated antibody
FITC标记的蛛毒素受体2抗体
| 英文名称 | Anti-LPHN2/FITC |
| 中文名称 | FITC标记的蛛毒素受体2抗体 |
| 别 名 | Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; CL2; KIAA0786; Latrophilin 1; Latrophilin 2; Latrophilin homolog 1; latrophilin homolog 2; LEC1; Lectomedin-1; LPH2; LPHH1; LPHN2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 160kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LPHN2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq, Jul 2008] Function: Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis. Subunit: Forms a heterodimer, consisting of a large extracellular region (p120) non-covalently linked to a seven-transmembrane moiety (p85) Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. Post-translational modifications: Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Contains 1 olfactomedin-like domain. Contains 1 SUEL-type lectin domain. Database links: Entrez Gene: 281278 Cow Entrez Gene: 100052932 Horse Entrez Gene: 23266 Human Entrez Gene: 100405265 Marmoset (common) Entrez Gene: 99633 Mouse Entrez Gene: 100013683 Opossum Entrez Gene: 100524685 Pig Entrez Gene: 100343149 Rabbit Entrez Gene: 171447 Rat Entrez Gene: 100551470 Turkey Omim: 607018 Human SwissProt: O97817 Cow SwissProt: O95490 Human SwissProt: Q8JZZ7 Mouse SwissProt: O88923 Rat Unigene: 24212 Human Unigene: 9776 Mouse Unigene: 12089 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这个基因编码A member of the latrophilin of G蛋白耦合受体家族（GPCR）。latrophilins May功能in both细胞粘附和信号转导。在实验以及非人类物种，内源性朊解理在半胱胺酸丰富的GPS（G蛋白耦合受体蛋白质加水分解的网站域名resulted in two亚基（）具有广泛的细胞外的N -末端细胞粘附亚基和亚基以及实质性相似to the促胰液素/ calcitonin family of being非共价结合的GPCRs）at the细胞膜。当几个成绩单变体have been描述，生物有效性of only one has been确定。[ provided by RefSeq，Jul 2008年]