Anti-CASP10 Polyclonal Antibody

K001601P-50ul	Solarbio	50ul	960.00元
K001601P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit CASP10 Polyclonal Antibody
别名	ALPS2;FLICE2;MCH4
应用	WB,IF
稀释比例	WB1:500-1:2000 IF1:50-1:200
交叉反应	Human
蛋白分子量	59kDa
Gene ID	843
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human CASP10
性状	Lyophilized or Liquid
Swiss Prot	Q92851
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.