Citrullinated Fibrinogen monoclonal antibody, clone 3D1
产品名称： Citrullinated Fibrinogen monoclonal antibody, clone 3D1
英文名称： Citrullinated Fibrinogen monoclonal antibody, clone 3D1
产品编号： MAB5303
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.
- Immunogen:
- A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.
- Host:
- Mouse
- Reactivity:
- Mouse
- Specificity:
- Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.
- Form:
- Lyophilized
- Isotype:
- IgG1
- Storage Buffer:
- Lyophilized from 10 mM ammonium bicarbonate buffer
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Application Image
- ELISA