细胞毒性T细胞抗原-4抗体-抗体-抗体-生物在线
北京索莱宝科技有限公司
细胞毒性T细胞抗原-4抗体

细胞毒性T细胞抗原-4抗体

商家询价

产品名称: 细胞毒性T细胞抗原-4抗体

英文名称: CTLA4

产品编号: bs-1179R

产品价格: null

产品产地: 北京

品牌商标: BIOSS

更新时间: 2025-10-24T13:32:05

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,

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This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.