CTCF polyclonal antibody (A01)
产品名称： CTCF polyclonal antibody (A01)
英文名称： CTCF polyclonal antibody (A01)
产品编号： H00010664-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant CTCF.
- Immunogen:
- CTCF (AAH14267, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
- Sequence:
- MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQV
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- CTCF polyclonal antibody (A01), Lot # 050727JC01 Western Blot analysis of CTCF expression in HL-60 ( Cat # L014V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 10664
- GeneBank Accession#:
- BC014267
- Protein Accession#:
- AAH14267
- Gene Name:
- CTCF
- Gene Alias:
- -
- Gene Description:
- CCCTC-binding factor (zinc finger protein)
- Omim ID:
- 604167
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq
- Other Designations:
- 11 zinc finger transcriptional repressor,11-zinc finger protein,CCCTC-binding factor,CTCFL paralog,transcriptional repressor CTCF