产品概述：Purified recombinant protein of Human F-box protein 32 (FBXO32), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

蛋白长度：A DNA sequence encoding human full-length FBXO32

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：24.5 kDa

通用名：FBXO32

总结：This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, 8M Urea, pH8.0.

别名：Fbx32; MAFbx