Anti-CASP12 Polyclonal Antibody

品牌：solarbio | 货号：K001602P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001602P-50ul	solarbio	50ul	960.00元
K001602P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-CASP12 Polyclonal Antibody
别名 CASP-12;CASP12P1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 39kDa
Gene ID 100506742
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CASP12
性状 液体
Public 
Immunogen 
Range A synthetic peptide of human CASP12
Subcellular 
Locations Endoplasmic reticulum
Swiss Prot Q6UXS9
克隆类型 Polyclonal Antibody
背景资料 Caspases are cysteine proteases that cleave C-terminal 
aspartic acid residues on their substrate molecules. This 
gene is most highly related to members of the ICE 
subfamily of caspases that process inflammatory cytokines. 
In rodents, the homolog of this gene mediates apoptosis in 
response to endoplasmic reticulum stress. However, in 
humans this gene contains a polymorphism for the 
presence or absence of a premature stop codon. The 
majority of human individuals have the premature stop 
codon and produce a truncated non-functional protein. 
The read-through codon occurs primarily in individuals of 
African descent and carriers have endotoxin hypo-
responsiveness and an increased susceptibility to severe 
sepsis. Several alternatively spliced transcript variants have 
been noted for this gene.

英文名称	Anti-CASP12 Polyclonal Antibody
别名	CASP-12;CASP12P1
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	39kDa
Gene ID	100506742
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human CASP12
性状	液体
Public Immunogen Range	A synthetic peptide of human CASP12
Subcellular Locations	Endoplasmic reticulum
Swiss Prot	Q6UXS9
克隆类型	Polyclonal Antibody
背景资料	Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo- responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.