Anti-MDM2 Polyclonal Antibody
产品名称: Anti-MDM2 Polyclonal Antibody
英文名称: Anti-MDM2 Polyclonal Antibody
产品编号: K001678P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-10-28T13:20:45
使用范围:
北京索莱宝科技有限公司
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Anti-MDM2 Polyclonal Antibody
品牌:Solarbio | 货号:K001678P
英文名称 Anti-MDM2 Polyclonal Antibody 宿主 Rabbit 别名 ACTFS;HDMX;hdm2 应用 WB IHC IF 稀释比例 WB 1:500-1:2000. IHC 1:50-1:200. IF 1:50-1:200. 交叉反应 Human Mouse Rat 蛋白分子量 55kDa 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 纯化方法 Affinity purification 亚型 IgG 免疫原 A synthetic peptide of human MDM2 Subcellular
LocationsCytoplasm Nucleus nucleolus nucleoplasm Swiss Prot Q00987 克隆类型 Polyclonal Antibody 背景资料 This gene encodes a nuclear-localized E3 ubiquitin ligase. The
encoded protein can promote tumor formation by targeting
tumor suppressor proteins, such as p53, for proteasomal
degradation. This gene is itself transcriptionally-regulated by
p53. Overexpression or amplification of this locus is detected
in a variety of different cancers. There is a pseudogene for
this gene on chromosome 2. Alternative splicing results in a
multitude of transcript variants, many of which may be
expressed only in tumor cells.

